Pathology - Tissue response to injury
2010/1: What is hypertrophy? Give examples of physiological and pathological hypertrophy.
2010/1: What is reperfusion injury? What are the proposed mechanisms of reperfusion injury?
2010/1: What systemic factors affect wound healing? What local factors impede wound healing?
2009/2: What cell types are present in chronic inflammation? What processes mediate the peristent accumulation of macrophages seen in chronic inflammation? What products are released by activated macrophages in chronic inflammation?
2009/2: Describe the process of skin wound healing by first intention.
2009/1: Describe the vascular changes that occur in acute inflammation. What are the causes of the increased vascular permeability?
2008/2: Describe the factors that affect wound healing. Describe the effect of an additional local or systemic factor.
2008/1: What are the differences between hyperplasia and hypertrophy? Describe the different types of hyperplasia and give an example of each.
2008/1: Describe the two different forms of pathological calcification and give an example of each. Describe the different principal pathological causes of hypercalcaemia, with some clinical examples.
2008/1: Describe how angiogenesis occurs.
2008/1: What are the phases involved in scar formation? What are the local triggers of fibroblast migration and proliferation at the site of an injury? What are the sources of these local triggers?
2007/2: What are the defining pathological characteristics of chronic inflammation? List some causes of chronic inflammation.
2007/1: Describe the order of events involved in healing by first intention. What important effects does platelet-derived growth factor have in relation to wound healing?
2007/1: Please describe the main vascular changes that occur with acute inflammation. What are the major mechanisms for the increased vascular permeability that occurs with inflammation?
2006/2: What is reperfusion injury? What are the proposed mechanisms of reperfusion injury?
2006/1: What is reperfusion injury after blood flow is restored to an ischaemic tissue? What mechanisms are involved?
2006/1: Describe the vascular changes in acute inflammation. What mechanisms cause increased vascular leakage in acute inflammation?
2005/2: What are the possible mechanisms for ischaemia-reperfusion injury? Describe how oxygen free radicals contribute to this injury.
2005/1: Describe the process of primary wound repair.
2005/1: How does a scar form? What factors influence scar formation? 2004/2: Describe the processes involved in healing by first intention.
2004/2: Describe the process of fibrosis and scar formation.
2004/2: What is the difference between dystrophic and metastatic calcification? What are the causes of metastatic calcification? What are the tissues most commonly affected by metastatic calcification?
2004/2: Describe the steps involved in angiogenesis.
2004/2: What is steatosis? Which organs are commonly involved in steatosis? What are the causes of hepatic steatosis?
2003/2: Describe the vascular response in acute inflammation. What are the mechanisms of increased vascular permeability in acute inflammation?
2003/1: Describe the process of peripheral nerve repair following traumatic injury. Describe what would be seen microscopically.