Pathology - Endocrine

2010/1: Classify haemolytic anaemias. Describe the common features of haemolytic anaemias. Give some important causes of intravascular haemolysis.

2009/2: What is the pathogenesis of diabetic ketoacidosis? What are the long-term complications of diabetes? Describe the stages in the development of Type I diabetes.

2009/1: What are the haematological and clinical effects of Von Willebrand's disease? Describe the types of Von Willebrand's disease.

2009/1: What is the function of vitamin K? What are the causes of Vitamin K deficiency?

2008/2: What is thyrotoxicosis? What are the clinical features of thyrotoxicosis? What are the main causes of thyrotoxicosis?

2008/2: What is the pathogenesis of Type I diabetes mellitus? What environmental factors may contribute to the development of Type I diabetes mellitus? How does genetic susceptibility contribute to the development of Type I diabetes mellitus?

2008/2: How are pituitary adenomas classified? What clinical syndromes may they produce?

2008/1: What is sickle cell disease? What are the major clinical features of sickle cell disease? What are the major precipitants for a sickle cell crisis in a prone individual?

2007/2: What is Von Willebrand's disease? What are the effects on clotting?

2007/2: What is Haemophilia A? Why do patients with Haemophilia A bleed? What is the association between clinical severity and Factor VIII levels?

2006/2: What is the pathogenesis of pernicious anaemia? What are the clinical manifestations of the disease?

2006/1: What defects in glucose handling characterise Type II diabetes mellitus? What are the main risk factors for the development of Type II diabetes mellitus? What are the main adverse effects of acute, severe, sustained hyperglycaemia?

2006/1: What are the main risk factors for the development of Type I diabetes mellitus? What is the sequence of events that leads to Type I diabetes mellitus? What aresome of the long-term complications of chronic hyperglycaemia?

2006/1: What are the characteristic clinical findings of Grave's disease? What is the pathogenesis?

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