Pathology - CNS

2010/1: Classify meningitis with examples of important causes. What are the likely organisms causing acute bacterial meningitis in different age groups? What are the typical CSF findings in acute bacterial meningitis?

2009/2: What are the clinical features of multiple sclerosis? What is the pathogenesis of multiple sclerosis? What might be found in the CSF of a patient with multiple sclerosis?

2007/2: What is the morphology of a berry aneurysm? What are the common sites of saccular aneurysms? What is the natural history of a ruptured berry aneurysm?

2007/2: What are some of the causes of dementia? Can you describe the pathogenesis of Alzheimer's disease?

2007/2: What are the causes of cerebral infarction?

2007/1: What is the most frequent cause of clinically significant subarachnoid haemorrhage? Where are saccular aneurysms commonly located? What is the aetiology of saccular aneurysms? What are the consequences of subarachnoid haemorrhage?

2007/1: What is multiple sclerosis? Describe the pathogeneis of multiple sclerosis. What are the typical cerebrospinal fluid changes found in multiple sclerosis?

2007/1: What are the different types of meningitis? What organisms commonly cause bacterial meningitis? How do the cerebrospinal fluid findings typically differ between acute bacterial and viral meningitis?

2006/2: Describe the organ system effects of lead poisoning. With regard to lead poisoning, what are the toxic mechanisms that operate?

2006/2: What are the pathological consequences of thiamine deficiency? In what areas of the CNS are lesions observed in Wernicke-Korsakoff's syndrome?

2003/1: What are the non-bacterial causes of meningitis? What are the typical CSF findings in viral meningitis? What are the common viral causes?

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