Pharmacology - Toxicology and Gastrointestinal

2009/2: In a poisoned patient what modalities are available for decontamination? How does activated charcoal work? Name some drugs that activated charcoal is not effective in absorbing. Name a drug where repeated doses of activated charcoal may assist in elimination of the drug.

2009/2: What is the mechanism of action of amphetamines? Describe the effects of amphetamines.

2008/2: Using examples, outline the mechanism of actions of the various types of laxatives.

2008/1: Explain the rationale for the use of octreotide in upper gastrointestinal bleeding. What are the pharmacokinetic differences between octreotide and somatostatin? What other agents may be useful in the prevention and treatment of upper GI bleeding?

2007/2: Name some of the ingredients in over-the-counter preparations that may cause toxicity. Give one example.

2007/2: What are the clinical uses of H1 antagonists? What are the major adverse effects? What are the significant potential drug interactions?

2006/2: What are the medical uses for St John's Wort? What are its important drug interactions?

2005/1: Describe the metabolism of methanol. What specific modalities of treatment are available for the treatment of severe methanol poisoning?

2004/2: How do you classify H1 antagonists? Describe the pharmacodynamics of promethazine. What are the important adverse reactions associated with this drug?

2003/2: Regarding glucagon, outline its pharmacodynamic effects and relate these to its clinical use.

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