Pharmacology - CNS II

2009/1: What are the clinical uses of chlorpromazine? What are the pharmacodynamic properties responsible for these effects? What are its adverse effects?

2009/1: What is the mechanism of action of ondansetron? What are the clinical uses of ondansetron? Name some side-effects of ondansetron.

2008/2: What is the mechanism of action of the tricyclic antidepressants? Describe the toxic effects in overdose and how are they mediated?

2008/2: What is the mechanism of action of the SSRI drugs? What receptor/channel effects lead to the SSRI side effect profile?

2008/2: Describe the mechanism of action of metoclopramide. List the adverse effects of metoclopramide.

2008/1: What classes of drugs can be used as antiemetics? List and explain the adverse effects of prochlorperazine.

2008/1: How do antidepressants exert their action? What are the relative advantages of different classes of antidepressants?

2007/2: What is the mechanism of action of clonazepam? What are the clinical uses of clonazepam? What properties make clonazepam an effective anticonvulsant?

2007/1: What is the mechanism of action of midazolam? What are the pharmacokinetics of midazolam? What are the pharmacodynamics of midazolam?

2007/1: What are the pharmacological characteristics of olanzepine? How does it differ from haloperidol?

2006/2: How does ondansetron work as an anti-emetic? What are the routes of administration and the dose of ondansetron?

2006/1: What are the advantages of olanzapine over the older antipsychotics? How does olanzapine compare with haloperidol in terms of sedation, hypotensive effect and extrapyramidal toxicity? What are the clinical conditions olanzapine is prescribed for?

2005/1: What adverse reactions can be associated with the use of antipsychotic agents?

2005/1: List the categories of antiemetic agents. Describe the mechanisms of action of three of these.

2004/2: What is the mechanism of action of midazolam? What is the drug antagonist for midazolam overdose? What adverse events may be associated with the use of flumazenil for midazolam toxicity?

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